Table 1

Cu and Zn isotopic compositions of the mouse brains


delta65Cu/63Cu
delta66Zn/64Zn
delta67Zn/64Zn

MF1
-0.59
-0.27
-0.47

-0.35
-0.30
-0.46

-0.33
-0.35
-0.54

-0.49
-0.29
-0.47

-0.43
-0.23
-0.30

-0.47
-0.29
-0.44

129
-0.29
-0.25
-0.47

-0.23
-0.42
-0.69

-0.78
-0.37
-0.56

-0.77
-0.32
-0.52

Fvb
-0.12
-0.37
-0.53

-0.16
-0.39
-0.52

-0.38
-0.32
-0.44

-0.3
-0.36
-0.51

C57
-0.35
-0.31
-0.46

-0.46
-0.41
-0.57

-0.7
-0.43
-0.59

-0.73
-0.48
-0.65

-0.42
-0.40
-0.60

PrP-KO (adult)
-0.56
-0.20
-0.26

-0.16
-0.19
-0.23

-0.14
-0.11
-0.13

-0.16
-0.02
-0.04

PrP-KO (newborn)
-0.33
-0.23
-0.30

-0.17
-0.19
-0.18

-0.1
0.00
0.07

-0.38
-0.10
-0.15

C4
-0.02
-0.15
-0.14

0.31
-0.22
-0.29

0.04
-0.21
-0.26

-0.09
-0.03
-0.06

TG20
0.18
0.08
0.12

-0.36
-0.04
-0.05

0.26
-0.09
-0.13

-0.44
-0.12
-0.17

-0.37
-0.25
-0.34

-0.58
-0.21
-0.28

Line Harry
-0.14
-0.26
-0.32

-0.17
-0.36
-0.46

-0.21
-0.25
-0.29

-0.46
-0.36
-0.5

The Cu and Zn isotope ratios of mice brains, expressed in the delta notation (as discussed in the text. The different samples are: MF1, 129, FvB and C57 BL/6 – wild-type mouse brains; PrP-KO (adult) prion protein deleted mouse brains, adult; PrP-KO (newborn) prion protein deleted mouse brains, new born; C4 – Cu binding domain of the prion protein deleted; TG20 – prion protein overexpressed; Line Harry – transgenic mouse brains with the genetic changes have no connection with Cu or Zn.

Büchl et al. Geochemical Transactions 2008 9:11   doi:10.1186/1467-4866-9-11